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Bioreactor Integrity™ PadReactor™

Bioreactor Integrity™ PadReactor™

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Belgique, Hoegaarden
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The Integrity™ PadReactor™ system is a single-use bioreactor specifically designed to fulfill the needs of cell culturists. It is perfectly suited to laboratory environments, process development centers, clinical material supply and flexible GMP manufacturing.

The PadReactor offers an open architecture controller platform, which gives the end user the opportunity to choose a preferred controller or use an existing control system.

The bioreactor vessel, which offers comparable functionality to classical stirred tank bioreactors, is a single-use bag integrating an internal paddle mixing and sparger system. This innovative bag design allows a non-invasive connection to the system. The paddle is enclosed in a medical grade ULDPE sleeve, made from the same contact material as the bag itself, and is coupled on top of the vessel with the mechanical mixing head.

The Integrity PadReactor utilizes disposable mixing bags made from Integrity TK8 bioprocess film. The product-contacting layer of TK8 film is blow-extruded in-house by ATMI under cleanroom conditions using medical-grade ultra low-density polyethylene resin. It is then laminated to create a gas barrier film of exceptional cleanliness, strength, and clarity that is animal derived component free (ADCF) and complies fully with USP Class VI requirements.

The Integrity PadReactor single-use bioreactor consists of the following:

Drive Unit: The flexible drive unit allows the system to cultivate cells in disposable bags. One drive unit can allow the user to mix in multiple disposable mixing bags of various sizes. Each system comes with the appropriate mixing stick for your container.

Mobile Retaining Tank: The purpose of the retaining tank is to support the mixing bag and provide mobility before and after operation. Various tank sizes and options are available.

Bioreactor Vessel: The reactor vessel uses an innovative bag design that allows a non-invasive connection to the mixer. Mixing is achieved when the integrated paddle/sparger inside the bag rotates within the bag.

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Bioreactor Integrity™ PadReactor™
Bioreactor Integrity™ PadReactor™
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